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A New Quinoline Derivative MS‐209 Reverses Multidrug Resistance and Inhibits Multiorgan Metastases by P‐glycoprotein‐expressing Human Small Cell Lung Cancer Cells

Development of distant metastases and acquired multidrug resistance (MDR) are major problems in therapy for human small cell lung cancer (SCLC). MS‐209 is a novel quinoline compound, which reverses P‐glycoprotein (P‐gp)‐mediated MDR. We previously reported that MS‐209 reversed in vitro MDR of human...

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Detalles Bibliográficos
Autores principales: Nokihara, Hiroshi, Yano, Seiji, Nishioka, Yasuhiko, Hanibuchi, Masaki, Higasida, Tsuyoshi, Tsuruo, Takashi, Sone, Saburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926782/
https://www.ncbi.nlm.nih.gov/pubmed/11473730
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01162.x