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TFAP2C regulates transcription in human naive pluripotency by opening enhancers

Naïve and primed pluripotent hESCs bear transcriptional similarity to pre- and post-implantation epiblast and thus constitute a developmental model for understanding the earliest pluripotent stages in human embryo development. To identify new transcription factors that differentially regulate the un...

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Detalles Bibliográficos
Autores principales: Pastor, William A., Liu, Wanlu, Chen, Di, Ho, Jamie, Kim, Rachel, Hunt, Timothy J., Lukianchikov, Anastasia, Liu, Xiaodong, Polo, Jose M., Jacobsen, Steven E., Clark, Amander T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926822/
https://www.ncbi.nlm.nih.gov/pubmed/29695788
http://dx.doi.org/10.1038/s41556-018-0089-0