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Anticancer Drug‐mediated Induction of Multidrug Resistance‐associated Genes and Protein Kinase C Isozymes in the T‐Lymphoblastoid Cell Line CCRF‐CEM and in Blasts from Patients with Acute Lymphoblastic Leukemias

The major determinants mediating drug resistance in acute lymphoblastic leukemias (ALL) unresponsive to chemotherapy, are still unclear. For example, it is still unknown whether selection or induction processes are responsible for drug resistance here or whether protein kinase C (PKC) isozymes contr...

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Detalles Bibliográficos
Autores principales: Beck, James F., Brügger, Dorothee, Brischwein, Klaus, Liu, Chao, Bader, Peter, Niethammer, Dietrich, Gekeler, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926830/
https://www.ncbi.nlm.nih.gov/pubmed/11509123
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01178.x