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Close Correlation of 1‐β‐D‐Arabinofuranosylcytosine 5′‐Triphosphate, an Intracellular Active Metabolite, to the Therapeutic Efficacy of N(4)‐Behenoyl‐1‐β‐D‐arabinofuranosylcytosine Therapy for Acute Myelogenous Leukemia

N(4)‐Behenoyl‐l‐β‐D‐arabinofuranosylcytosine (BHAC), a prodrug of 1‐β ‐D‐arabinofuranosylcy‐tosine, is used effectively for the treatment of leukemia in Japan. BHAC therapy may be more effective if it is delivered in conjunction with monitoring of 1‐β ‐D‐arabinofuranosylcytosine 5′‐tri‐phosphate (ar...

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Detalles Bibliográficos
Autores principales: Yamauchi, Takahiro, Kawai, Yasukazu, Goto, Nobuyuki, Kishi, Shinji, Imamura, Shin, Yoshida, Akira, Urasaki, Yoshimasa, Fukushima, Toshihiro, Iwasaki, Hiromichi, Tsutani, Hiroshi, Masada, Mikio, Ueda, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926845/
https://www.ncbi.nlm.nih.gov/pubmed/11572766
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01188.x