Cargando…
Close Correlation of 1‐β‐D‐Arabinofuranosylcytosine 5′‐Triphosphate, an Intracellular Active Metabolite, to the Therapeutic Efficacy of N(4)‐Behenoyl‐1‐β‐D‐arabinofuranosylcytosine Therapy for Acute Myelogenous Leukemia
N(4)‐Behenoyl‐l‐β‐D‐arabinofuranosylcytosine (BHAC), a prodrug of 1‐β ‐D‐arabinofuranosylcy‐tosine, is used effectively for the treatment of leukemia in Japan. BHAC therapy may be more effective if it is delivered in conjunction with monitoring of 1‐β ‐D‐arabinofuranosylcytosine 5′‐tri‐phosphate (ar...
Autores principales: | Yamauchi, Takahiro, Kawai, Yasukazu, Goto, Nobuyuki, Kishi, Shinji, Imamura, Shin, Yoshida, Akira, Urasaki, Yoshimasa, Fukushima, Toshihiro, Iwasaki, Hiromichi, Tsutani, Hiroshi, Masada, Mikio, Ueda, Takanori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926845/ https://www.ncbi.nlm.nih.gov/pubmed/11572766 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01188.x |
Ejemplares similares
-
Monitoring of Intracellular l‐βD‐Arabinofuranosylcytosine 5′‐Triphosphate in 1‐β‐D‐Arabinofuranosylcytosine Therapy at Low and Conventional Doses
por: Yamauchi, Takahiro, et al.
Publicado: (2001) -
l‐β‐D‐Arabinofuranosylcytosine Is Cytotoxic in Quiescent Normal Lymphocytes Undergoing DNA Excision Repair
por: Yamauchi, Takahiro, et al.
Publicado: (2002) -
Antitumor Activity and Pharmacology of 1‐β‐D‐Arabinofuranosylcytosine‐5′‐stearylphosphate: An Orally Active Derivative of 1‐β‐D‐Arabinofuranosylcytosine
por: Kodama, Kenjiro, et al.
Publicado: (1989) -
Modulation of the Effect of l‐β‐D‐Arabinofuranosylcytosine by 6‐Mercaptopurine in L1210 Cells
por: Kawai, Yasukazu, et al.
Publicado: (1994) -
Metabolism and Toxicity of Electroporated 1‐β‐d‐Arabinofuranosylcytosine Triphosphate in a Human Leukemia Cell Line
por: Kubota, Masaru, et al.
Publicado: (1990)