Augmented Adriamycin Sensitivity in Cells Transduced with an Antisense Tumor Necrosis Factor Gene Is Mediated by Caspase‐3 Downstream from Reactive Oxygen Species

While transduction of an antisense tumor necrosis factor (TNF) gene sequence can augment the cytotoxicity of adriamycin (ADM) in human cancer cells, the specific effect of introducing this sequence on the signal transduction pathway leading to cell death remains unclear. In ADM‐resistant pancreatic...

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Detalles Bibliográficos
Autores principales: Sasaki, Masahiro, Kobayashi, Daisuke, Watanabe, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926847/
https://www.ncbi.nlm.nih.gov/pubmed/11572767
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01189.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926847/
https://www.ncbi.nlm.nih.gov/pubmed/11572767
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01189.x

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