Heterogeneous Breakpoints on the Immunoglobulin Genes Are Involved in Fusion with the 5′ Region of BCL2 in B‐Cell Tumors

The 5′flanking region of the BCL2 gene (5′‐BCL2) is a breakpoint cluster of rearrangements with immunoglobulin genes (IGs). In contrast to t(14;18)(q32;q21) affecting the 3’region of BCL2, 5′‐BCL2 can fuse to not only the heavy chain gene (IGH), but also two light chain gene (IGL) loci. We report he...

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Detalles Bibliográficos
Autores principales: Yonetani, Noboru, Ueda, Chiyoko, Akasaka, Takashi, Nishikori, Momoko, Uchiyama, Takashi, Ohno, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926849/
https://www.ncbi.nlm.nih.gov/pubmed/11572760
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01183.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926849/
https://www.ncbi.nlm.nih.gov/pubmed/11572760
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01183.x

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