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Lack of a Dose‐response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline or N‐Nitrosodiethylamine

For a long period, it has been generally considered that carcinogens, particularly genotoxic ones, have no threshold in exerting their potential for cancer induction. However, the non‐threshold theory can be challenged with regard to assessment of cancer risk to humans. Here we show that a food‐deri...

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Detalles Bibliográficos
Autores principales: Fukushima, Shoji, Wanibuchi, Hideki, Morimura, Keiichirou, Wei, Min, Nakae, Dai, Konishi, Yoichi, Tsuda, Hiroyuki, Uehara, Nobuaki, Imaida, Katsumi, Shirai, Tomoyuki, Tatematsu, Masae, Tsukamoto, Tetsuya, Hirose, Masao, Furukawa, Fumio, Wakabayashi, Keiji, Totsuka, Yukari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926877/
https://www.ncbi.nlm.nih.gov/pubmed/12417036
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01208.x