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Frequent Epigenetic Silencing of the p16 Gene in Non‐small Cell Lung Cancers of Tobacco Smokers

Epidemiological studies have demonstrated a causal link between tobacco smoking and lung cancer. We investigated the association between inactivation of the p16 gene and tobacco smoking in 51 non‐small cell lung cancers (NSCLCs). Aberrations of the p16 gene were studied by PCR single‐strand conforma...

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Detalles Bibliográficos
Autores principales: Yanagawa, Naoki, Tamura, Gen, Oizumi, Hiroyuki, Takahashi, Nobumasa, Shimazaki, Yasuhisa, Motoyama, Teiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926878/
https://www.ncbi.nlm.nih.gov/pubmed/12417040
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01212.x