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Development of Gene Therapy Using Prostate‐specific Membrane Antigen Promoter/Enhancer with Cre Recombinase/LoxP System for Prostate Cancer Cells under Androgen Ablation Condition

To enhance the efficacy of suicide gene therapy for prostate cancer under androgen deprivation, we designed a promoter system that consists of the prostate‐specific membrane antigen (PSMA) promoter/enhancer (PEPM) and Cre‐loxP DNA recombination system. We constructed two kinds of plasmids. One plasm...

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Detalles Bibliográficos
Autores principales: Ikegami, Shusei, Tadakuma, Takushi, Suzuki, Satoshi, Yoshimura, Ichiro, Asano, Tomohiko, Hayakawa, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926883/
https://www.ncbi.nlm.nih.gov/pubmed/12417046
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01218.x