Cloning of the 5’Upstream Region of the Rat p16 Gene and Its Role in Silencing

Hypermethylation of the 5’upstream region (5’region) of the human p16(CDKN2A) (p16) gene is known to cause silencing, which is involved in a wide range of human cancers. For the rat p16 gene, its 5’region has not been cloned, and it is uncertain whether surrogate use of exon la is adequate for analy...

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Detalles Bibliográficos
Autores principales: Abe, Masanobu, Okochi, Eriko, Kuramoto, Takashi, Kaneda, Atsushi, Takato, Tsuyoshi, Sugimura, Takashi, Ushijima, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926886/
https://www.ncbi.nlm.nih.gov/pubmed/12417039
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01211.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926886/
https://www.ncbi.nlm.nih.gov/pubmed/12417039
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01211.x

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