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Cloning of the 5’Upstream Region of the Rat p16 Gene and Its Role in Silencing
Hypermethylation of the 5’upstream region (5’region) of the human p16(CDKN2A) (p16) gene is known to cause silencing, which is involved in a wide range of human cancers. For the rat p16 gene, its 5’region has not been cloned, and it is uncertain whether surrogate use of exon la is adequate for analy...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926886/ https://www.ncbi.nlm.nih.gov/pubmed/12417039 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01211.x |