Cargando…

Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies

Hemostatic defects are treated using coagulation factors; however, clot formation also requires a procoagulant phospholipid (PL) surface. Here, we show that innate immune cell–derived enzymatically oxidized phospholipids (eoxPL) termed hydroxyeicosatetraenoic acid–phospholipids (HETE-PLs) restore he...

Descripción completa

Detalles Bibliográficos
Autores principales:	Slatter, David A., Percy, Charles L., Allen-Redpath, Keith, Gajsiewicz, Joshua M., Brooks, Nick J., Clayton, Aled, Tyrrell, Victoria J., Rosas, Marcela, Lauder, Sarah N., Watson, Andrew, Dul, Maria, Garcia-Diaz, Yoel, Aldrovandi, Maceler, Heurich, Meike, Hall, Judith, Morrissey, James H., Lacroix-Desmazes, Sebastien, Delignat, Sandrine, Jenkins, P. Vincent, Collins, Peter W., O’Donnell, Valerie B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926910/ https://www.ncbi.nlm.nih.gov/pubmed/29563336 http://dx.doi.org/10.1172/jci.insight.98459

Ejemplares similares

Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity
por: Allen-Redpath, Keith, et al.
Publicado: (2019)

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo
por: Lauder, Sarah N., et al.
Publicado: (2017)

Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation
por: Aldrovandi, Maceler, et al.
Publicado: (2013)

Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells
por: Aldrovandi, Maceler, et al.
Publicado: (2018)

DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression
por: Aldrovandi, Maceler, et al.
Publicado: (2017)

Oxidized PLs and Vascular Inflammation
por: Aldrovandi, Maceler, et al.
Publicado: (2013)

Corrigendum to “Specific oxygenation of plasma membrane phospholipids by Pseudomonas aeruginosa lipoxygenase induces structural and functional alterations in mammalian cells” [BBA-Mol. Cell Biol. Volume 1863/2, Pages 152–164]
por: Aldrovandi, Maceler, et al.
Publicado: (2020)

Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A(3), a Neutrophil-activating Eicosanoid
por: Hinz, Christine, et al.
Publicado: (2016)

The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles
por: Rosas, Marcela, et al.
Publicado: (2020)

Ferroptosis: the Good, the Bad and the Ugly
por: Aldrovandi, Maceler, et al.
Publicado: (2020)

Inhibition of thrombin generation in human plasma by phospholipid transfer protein
por: Deguchi, Hiroshi, et al.
Publicado: (2015)

Phosphoproteomic Analysis of Platelets Activated by Pro-Thrombotic Oxidized Phospholipids and Thrombin
por: Zimman, Alejandro, et al.
Publicado: (2014)

Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A(2) as a Regulator of Mitochondrial Bioenergetics during Activation
por: Slatter, David A., et al.
Publicado: (2016)

Prevention of the anti-factor VIII memory B-cell response by inhibition of Bruton tyrosine kinase in experimental hemophilia A
por: Delignat, Sandrine, et al.
Publicado: (2019)

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation
por: Thomas, Christopher P., et al.
Publicado: (2010)

Ability of Polyphosphate and Nucleic Acids to Trigger Blood Clotting: Some Observations and Caveats
por: Smith, Stephanie A., et al.
Publicado: (2018)

Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance
por: Mimoun, Angelina, et al.
Publicado: (2020)

Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells
por: Karnam, Anupama, et al.
Publicado: (2020)

The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice.
por: Bou-Jaoudeh, Melissa, et al.
Publicado: (2023)

Removal of Mannose-Ending Glycan at Asn(2118) Abrogates FVIII Presentation by Human Monocyte-Derived Dendritic Cells
por: Delignat, Sandrine, et al.
Publicado: (2020)

Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis
por: Heurich, Meike, et al.
Publicado: (2021)

Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization
por: Soria-Tiedemann, Mariana, et al.
Publicado: (2022)

Deciphering the coagulation profile through the dynamics of thrombin activity
por: de Laat-Kremers, Romy M. W., et al.
Publicado: (2020)

Thrombin generation: a global coagulation procedure to investigate hypo- and hyper-coagulability
por: Tripodi, Armando
Publicado: (2020)

Complement C3 is a novel modulator of the anti-factor VIII immune response
por: Rayes, Julie, et al.
Publicado: (2018)

Phospholipid-mediated exfoliation as a facile preparation method for graphene suspensions
por: Williams, Aled T., et al.
Publicado: (2018)

Tissue Factor Residues That Putatively Interact with Membrane Phospholipids
por: Ke, Ke, et al.
Publicado: (2014)

Novel Keto-phospholipids Are Generated by Monocytes and Macrophages, Detected in Cystic Fibrosis, and Activate Peroxisome Proliferator-activated Receptor-γ
por: Hammond, Victoria J., et al.
Publicado: (2012)

Thrombin and factor Xa link the coagulation system with liver fibrosis
por: Dhar, Ameet, et al.
Publicado: (2018)

Pathogenic immune response to therapeutic factor VIII: exacerbated response or failed induction of tolerance?
por: Varthaman, Aditi, et al.
Publicado: (2019)

Thrombin generation abnormalities in commonly encountered platelet function disorders
por: Sharma, Tanmya, et al.
Publicado: (2021)

Post-Transcriptional Regulation of BCL2 mRNA by the RNA-Binding Protein ZFP36L1 in Malignant B Cells
por: Zekavati, Anna, et al.
Publicado: (2014)

STUDIES ON BLOOD COAGULATION : II. THE FORMATION OF FIBRIN FROM THROMBIN AND FIBRINOGEN
por: Eagle, Harry
Publicado: (1935)

STUDIES ON BLOOD COAGULATION : I. THE RÔLE OF PROTHROMBIN AND OF PLATELETS IN THE FORMATION OF THROMBIN
por: Eagle, Harry
Publicado: (1935)

Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond
por: Danckwardt, Sven, et al.
Publicado: (2013)

Coagulation Factor XII Levels and Intrinsic Thrombin Generation in Multiple Sclerosis
por: Ziliotto, Nicole, et al.
Publicado: (2018)

Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood
por: Konrath, Sandra, et al.
Publicado: (2022)

Emerging benefits of Fc fusion technology in the context of recombinant factor VIII replacement therapy
por: Meeks, Shannon L., et al.
Publicado: (2020)

Editorial: Tolerating Factor VIII: Novel Strategies to Prevent and Reverse Neutralizing Anti-FVIII Antibodies
por: Lacroix-Desmazes, Sébastien, et al.
Publicado: (2021)

STUDIES ON BLOOD COAGULATION : III. ON THE CONSTANCY OF THE HYDROGEN ION CONCENTRATION DURING THE COAGULATION OF FIBRINOGEN BY THROMBIN
por: Eagle, Harry, et al.
Publicado: (1935)

Cannot write session to /tmp/vufind_sessions/sess_rpdhu4uimapd9563oku397mn74