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Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis

Alterations in ectopic lipid deposition and circulating lipids are major risk factors for developing cardiometabolic diseases. Angiopoietin-like protein 4 (ANGPTL4), a protein that inhibits lipoprotein lipase (LPL), controls fatty acid (FA) uptake in adipose and oxidative tissues and regulates circu...

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Detalles Bibliográficos
Autores principales: Aryal, Binod, Singh, Abhishek K., Zhang, Xinbo, Varela, Luis, Rotllan, Noemi, Goedeke, Leigh, Chaube, Balkrishna, Camporez, Joao-Paulo, Vatner, Daniel F., Horvath, Tamas L., Shulman, Gerald I., Suárez, Yajaira, Fernández-Hernando, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926923/
https://www.ncbi.nlm.nih.gov/pubmed/29563332
http://dx.doi.org/10.1172/jci.insight.97918