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Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis
Alterations in ectopic lipid deposition and circulating lipids are major risk factors for developing cardiometabolic diseases. Angiopoietin-like protein 4 (ANGPTL4), a protein that inhibits lipoprotein lipase (LPL), controls fatty acid (FA) uptake in adipose and oxidative tissues and regulates circu...
Autores principales: | Aryal, Binod, Singh, Abhishek K., Zhang, Xinbo, Varela, Luis, Rotllan, Noemi, Goedeke, Leigh, Chaube, Balkrishna, Camporez, Joao-Paulo, Vatner, Daniel F., Horvath, Tamas L., Shulman, Gerald I., Suárez, Yajaira, Fernández-Hernando, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926923/ https://www.ncbi.nlm.nih.gov/pubmed/29563332 http://dx.doi.org/10.1172/jci.insight.97918 |
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