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Estrone and 17β‐Estradiol Reverse Breast Cancer Resistance Protein‐mediated Multidrug Resistance

Breast cancer resistance protein (BCRP), an adenosine triphosphate‐binding cassette transporter, confers resistance to a series of anticancer reagents, including mitoxantrone, SN‐38 and topotecan. In the present study, we found that estrone and l7β‐estradiol potentiated the cytotoxicity of mitoxantr...

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Detalles Bibliográficos
Autores principales: Imai, Yasuo, Tsukahara, Satomi, Ishikawa, Etsuko, Tsuruo, Takashi, Sugimoto, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926974/
https://www.ncbi.nlm.nih.gov/pubmed/11927002
http://dx.doi.org/10.1111/j.1349-7006.2002.tb02162.x