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Autologous Fixed Tumor Vaccine: A Formulation with Cytokine‐microparticles for Protective Immunity against Recurrence of Human Hepatocellular Carcinoma
We developed a tumor vaccine consisting of fixed hepatocellular carcinoma (HCC) cells/tissue fragments, biodegradable microparticles encapsulating granulocyte‐macrophage‐colony stimulating factor and interleukin‐2, and an adjuvant. The vaccine protected 33% of syngeneic mice from HCC cell challenge....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927015/ https://www.ncbi.nlm.nih.gov/pubmed/11985784 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01265.x |