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Autologous Fixed Tumor Vaccine: A Formulation with Cytokine‐microparticles for Protective Immunity against Recurrence of Human Hepatocellular Carcinoma

We developed a tumor vaccine consisting of fixed hepatocellular carcinoma (HCC) cells/tissue fragments, biodegradable microparticles encapsulating granulocyte‐macrophage‐colony stimulating factor and interleukin‐2, and an adjuvant. The vaccine protected 33% of syngeneic mice from HCC cell challenge....

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Detalles Bibliográficos
Autores principales: Peng, Bao Gang, Liu, Shu Qin, Kuang, Ming, He, Qiang, Totsuka, Saeri, Huang, Lan, Huang, Jiefu, Lu, Ming‐De, Liang, Li‐Jiang, Leong, Kam W., Ohno, Tadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927015/
https://www.ncbi.nlm.nih.gov/pubmed/11985784
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01265.x

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