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Inhibition of Nucleotide Excision Repair by Fludarabine in Normal Lymphocytes in vitro, Measured by the Alkaline Single Cell Gel Electrophoresis (Comet) Assay

Alkylating agents or platinum analogues initiate several excision repair mechanisms, which involve incision of the DNA strand, excision of the damaged nucleotide, gap filling by DNA resynthesis, and rejoining by ligation. The previous study described that nucleotide excision repair permitted incorpo...

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Detalles Bibliográficos
Autores principales: Yamauchi, Takahiro, Kawai, Yasukazu, Ueda, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927026/
https://www.ncbi.nlm.nih.gov/pubmed/12036453
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01292.x