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Induction of Intestinal Tumors and Lymphomas in C57BL/6N Mice by a Food‐borne Carcinogen, 2‐Amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine

2‐Amino‐l‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) is the most abundant heterocyclic amine contained in cooked meat and fish. Although PhIP has been demonstrated to induce various types of tumors in rats, lymphomas predominated in mice using the CDF1 strain. To investigate the carcinogenic activ...

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Detalles Bibliográficos
Autores principales: Ochiai, Masako, Imai, Hiroshi, Sugimura, Takashi, Nagao, Minako, Nakagama, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927040/
https://www.ncbi.nlm.nih.gov/pubmed/12036442
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01281.x