Hammerhead Ribozyme against γ‐Glutamylcysteine Synthetase Attenuates Resistance to Ionizing Radiation and Cisplatin in Human T98G Glioblastoma Cells

Glioblastoma cells are highly malignant and show resistance to ionizing radiation, as well as anti‐cancer drugs. This resistance to cancer therapy is often associated with a high concentration of glutathione (GSH). In this study, the effect of continuous down‐regulation of γ‐glutamylcysteine synthet...

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Detalles Bibliográficos
Autores principales: Tani, Masaharu, Goto, Shinji, Kamada, Kensaku, Mori, Katsuharu, Urata, Yoshishige, Ihara, Yoshito, Kijima, Hiroshi, Ueyama, Yoshito, Shibata, Shobu, Kondo, Takahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927042/
https://www.ncbi.nlm.nih.gov/pubmed/12079521
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01311.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927042/
https://www.ncbi.nlm.nih.gov/pubmed/12079521
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01311.x

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