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Dose of Adenoviral Vectors Expressing Interleukin‐2 Plays an Important Role in Combined Gene Therapy with Cytosine Deaminase/5–Fluorocytosine: Preclinical Consideration
Using a syngeneic murine model, we investigated the therapeutic efficacy of combined gene therapy using adenoviral vectors expressing murine interleukin‐2 (AdmIL‐2) and Escherichia coli cytosine deaminase (AdCD). In a subcutaneous tumor model, tumor‐bearing mice were treated with an intratumoral inj...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927048/ https://www.ncbi.nlm.nih.gov/pubmed/12079520 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01310.x |