Transgenic Rats Carrying Human c‐Ha‐ras Proto‐oncogene Are Highly Susceptible to N‐Nitrosomethylbenzylamine Induction of Esophageal Tumorigenesis

A transgenic rat line carrying three copies of the human c‐Ha‐ras proto‐oncogene, including its own promoter region, has been established in our laboratory (Hras128 rats), and shown to be highly susceptible to induction of mammary and urinary bladder tumors. Mutation analysis of induced lesions indi...

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Detalles Bibliográficos
Autores principales: Asamoto, Makoto, Toriyama‐Baba, Hiroyasu, Ohnishi, Takamasa, Naito, Akihiro, Ota, Tomonori, Ando, Akira, Ochiya, Takahiro, Tsuda, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927067/
https://www.ncbi.nlm.nih.gov/pubmed/12149139
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01315.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927067/
https://www.ncbi.nlm.nih.gov/pubmed/12149139
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01315.x

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