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Ratio of Expression of p16(INK4a) to p14(ARF) Correlates with the Progression of Non‐small Cell Lung Cancer

The CDKN2 gene is located on the short arm of chromosome 9p and encodes two unrelated proteins, p16(INK4a) and p14(ARF), through the use of independent first exons and shared exons 2 and 3. p16(INK4a) is a cyclin‐dependent kinase inhibitor, whereas p14(ARF) regulates the cell cycle through a p53 and...

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Detalles Bibliográficos
Autores principales: Moriyama, Satoru, Nakashima, Yoshiaki, Yano, Motoki, Kaji, Masahiro, Yamakawa, Yosuke, Toyama, Tatsuya, Yamashita, Hiroko, Iwase, Hirotaka, Sasaki, Hidefumi, Saito, Yushi, Kiriyama, Masanobu, Kato, Jyoji, Fujii, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927070/
https://www.ncbi.nlm.nih.gov/pubmed/12149144
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01320.x