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An Anti‐GD2 Monoclonal Antibody Enhances Apoptotic Effects of Anti‐cancer Drugs against Small Cell Lung Cancer Cells via JNK (c‐Jun Terminal Kinase) Activation

Small cell lung cancer (SCLC) cell lines specifically express ganglioside GD2, and anti‐GD2 monoclonal antibodies (mAbs) caused suppression of cell growth and induced apoptosis of SCLC cells with single use. Here, enhancement of the cytotoxic effects of various anti‐cancer drugs with an anti‐GD2 mAb...

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Detalles Bibliográficos
Autores principales: Yoshida, Shoko, Kawaguchi, Haruhiko, Sato, Shigeki, Ueda, Ryuzo, Furukawa, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927075/
https://www.ncbi.nlm.nih.gov/pubmed/12149148
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01324.x