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Estradiol Stabilizes p53 Protein in Breast Cancer Cell Line, MCF–7

Overexpression of the oncoprotein MDM2, an important regulator of the p53 tumor suppressor protein, is often observed in breast cancer tissues and cell lines, particularly in those which express estrogen receptor a (ERa). In MCF–7 breast cancer cell line possessing wild‐type p53, ERa, and overexpres...

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Detalles Bibliográficos
Autores principales: Okumura, Naoki, Saji, Shigehira, Eguchi, Hidetaka, Hayashi, Shin‐ichi, Saji, Shigetoyo, Nakashima, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927107/
https://www.ncbi.nlm.nih.gov/pubmed/12716463
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01331.x