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Colorectal Cancers with both p16 and p14 Methylation Show Invasive Characteristics

Recent studies indicated that p16 and p14 inactivation owing to promoter methylation was important for colorectal tumorigenesis. In this study, we examined the methylation status of these genes in 86 primary colorectal cancers using methylation‐specific PCR (MSP) and correlated the results with the...

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Detalles Bibliográficos
Autores principales: Hibi, Kenji, Nakayama, Hiroshi, Koike, Masahiko, Kasai, Yasushi, Ito, Katsuki, Akiyama, Seiji, Nakao, Akimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927110/
https://www.ncbi.nlm.nih.gov/pubmed/12716465
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01333.x