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Sequential Involvement of Two Distinct CD4(+) Regulatory T Cells during the Course of Transplantable Tumor Growth and Protection from 3–Methylcholanthrene‐induced Tumorigenesis by CD25–depletion

The involvement of two phenotypically different regulatory T cells in different stages of tumor growth was investigated. Treatment of BALB/c mice with anti‐CD25 monoclonal antibody (mAb) (PC61), but not anti‐CD4 mAb (GK1.5) before RL male 1 or Meth A inoculation caused tumor rejection. On the other...

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Detalles Bibliográficos
Autores principales: Tawara, Isao, Take, Yutaka, Uenaka, Akiko, Noguchi, Yuji, Nakayama, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927116/
https://www.ncbi.nlm.nih.gov/pubmed/12716469
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01337.x