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Allelic Losses in Mouse Skin Tumors Induced by γ‐Irradiation of p53 Heterozygotes

Skin tumors were induced by γ‐irradiation in F(1) mice between C3H/He or BALB/c and MSM carrying a p53‐deficient allele. The incidence was 39.1% (34/87) in p53 (KO/+) mice of the C3H/MSM genetic background and 14.3% (19/133) in those of the BALB/MSM background. Interestingly, most of the tumors (82%...

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Detalles Bibliográficos
Autores principales: Miyazawa, Tomonori, Sato, Hiroki, Hatakeyama, Katsuyoshi, Kitagawa, Tomoyuki, Kominami, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927138/
https://www.ncbi.nlm.nih.gov/pubmed/12359052
http://dx.doi.org/10.1111/j.1349-7006.2002.tb02475.x