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Allelic Losses in Mouse Skin Tumors Induced by γ‐Irradiation of p53 Heterozygotes
Skin tumors were induced by γ‐irradiation in F(1) mice between C3H/He or BALB/c and MSM carrying a p53‐deficient allele. The incidence was 39.1% (34/87) in p53 (KO/+) mice of the C3H/MSM genetic background and 14.3% (19/133) in those of the BALB/MSM background. Interestingly, most of the tumors (82%...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927138/ https://www.ncbi.nlm.nih.gov/pubmed/12359052 http://dx.doi.org/10.1111/j.1349-7006.2002.tb02475.x |