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β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

Innate immune memory is the phenomenon whereby innate immune cells such as monocytes or macrophages undergo functional reprogramming after exposure to microbial components such as lipopolysaccharide (LPS). We apply an integrated epigenomic approach to characterize the molecular events involved in LP...

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Detalles Bibliográficos
Autores principales: Novakovic, Boris, Habibi, Ehsan, Wang, Shuang-Yin, Arts, Rob J.W., Davar, Robab, Megchelenbrink, Wout, Kim, Bowon, Kuznetsova, Tatyana, Kox, Matthijs, Zwaag, Jelle, Matarese, Filomena, van Heeringen, Simon J., Janssen-Megens, Eva M., Sharifi, Nilofar, Wang, Cheng, Keramati, Farid, Schoonenberg, Vivien, Flicek, Paul, Clarke, Laura, Pickkers, Peter, Heath, Simon, Gut, Ivo, Netea, Mihai G., Martens, Joost H.A., Logie, Colin, Stunnenberg, Hendrik G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927328/
https://www.ncbi.nlm.nih.gov/pubmed/27863248
http://dx.doi.org/10.1016/j.cell.2016.09.034