Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers

The anthelmintic praziquantel (±PZQ) serves as a highly effective antischistosomal therapy. ±PZQ causes a rapid paralysis of adult schistosome worms and deleterious effects on the worm tegument. In addition to these activities against the parasite, ±PZQ also modulates host vascular tone in blood ves...

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Detalles Bibliográficos
Autores principales: Gunaratne, Gihan S., Yahya, Nawal A., Dosa, Peter I., Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927461/
https://www.ncbi.nlm.nih.gov/pubmed/29668703
http://dx.doi.org/10.1371/journal.pntd.0006420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927461/
https://www.ncbi.nlm.nih.gov/pubmed/29668703
http://dx.doi.org/10.1371/journal.pntd.0006420

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