Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation

Mitochondrial function affects many aspects of cellular physiology, and, most recently, its role in epigenetics has been reported. Mechanistically, how mitochondrial function alters DNA methylation patterns in the nucleus remains ill defined. Using a cell culture model of induced mitochondrial DNA (...

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Detalles Bibliográficos
Autores principales: Lozoya, Oswaldo A., Martinez-Reyes, Inmaculada, Wang, Tianyuan, Grenet, Dagoberto, Bushel, Pierre, Li, Jianying, Chandel, Navdeep, Woychik, Richard P., Santos, Janine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927466/
https://www.ncbi.nlm.nih.gov/pubmed/29668680
http://dx.doi.org/10.1371/journal.pbio.2005707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927466/
https://www.ncbi.nlm.nih.gov/pubmed/29668680
http://dx.doi.org/10.1371/journal.pbio.2005707

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