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Dectin-1/2–induced autocrine PGE(2) signaling licenses dendritic cells to prime Th2 responses

The molecular mechanisms through which dendritic cells (DCs) prime T helper 2 (Th2) responses, including those elicited by parasitic helminths, remain incompletely understood. Here, we report that soluble egg antigen (SEA) from Schistosoma mansoni, which is well known to drive potent Th2 responses,...

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Detalles Bibliográficos
Autores principales: Kaisar, Maria M. M., Ritter, Manuel, del Fresno, Carlos, Jónasdóttir, Hulda S., van der Ham, Alwin J., Pelgrom, Leonard R., Schramm, Gabriele, Layland, Laura E., Sancho, David, Prazeres da Costa, Clarissa, Giera, Martin, Yazdanbakhsh, Maria, Everts, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927467/
https://www.ncbi.nlm.nih.gov/pubmed/29668708
http://dx.doi.org/10.1371/journal.pbio.2005504