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Actin polymerization in the endosomal pathway, but not on the Coxiella-containing vacuole, is essential for pathogen growth

Coxiella burnetii is an intracellular bacterium that replicates within an expansive phagolysosome-like vacuole. Fusion between the Coxiella-containing vacuole (CCV) and late endosomes/multivesicular bodies requires Rab7, the HOPS tethering complex, and SNARE proteins, with actin also speculated to p...

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Detalles Bibliográficos
Autores principales: Miller, Heather E., Larson, Charles L., Heinzen, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927470/
https://www.ncbi.nlm.nih.gov/pubmed/29668757
http://dx.doi.org/10.1371/journal.ppat.1007005