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Actin polymerization in the endosomal pathway, but not on the Coxiella-containing vacuole, is essential for pathogen growth
Coxiella burnetii is an intracellular bacterium that replicates within an expansive phagolysosome-like vacuole. Fusion between the Coxiella-containing vacuole (CCV) and late endosomes/multivesicular bodies requires Rab7, the HOPS tethering complex, and SNARE proteins, with actin also speculated to p...
Autores principales: | Miller, Heather E., Larson, Charles L., Heinzen, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927470/ https://www.ncbi.nlm.nih.gov/pubmed/29668757 http://dx.doi.org/10.1371/journal.ppat.1007005 |
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