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CD44v6 as innovative sarcoma target for CAR-redirected CIK cells

Purpose of our study was to explore a new immunotherapy for high grade soft tissue sarcomas (STS) based on cytokine-induced killer cells (CIK) redirected with a chimeric antigen receptor (CAR) against the tumor-promoting antigen CD44v6. We aimed at generating bipotential killers, combining the CAR s...

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Detalles Bibliográficos
Autores principales: Leuci, V., Casucci, G. M., Grignani, G., Rotolo, R., Rossotti, U., Vigna, E., Gammaitoni, L., Mesiano, G., Fiorino, E., Donini, C., Pisacane, A., ambrosio, L. D., Pignochino, Y., Aglietta, M., Bondanza, A., Sangiolo, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927525/
https://www.ncbi.nlm.nih.gov/pubmed/29721373
http://dx.doi.org/10.1080/2162402X.2017.1423167