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Prognosis of ovarian cancer is associated with effector memory CD8(+) T cell accumulation in ascites, CXCL9 levels and activation-triggered signal transduction in T cells

The accumulation of intratumoral CD8(+) T cells is associated with the survival of high grade serous ovarian carcinoma patients, but it is unclear which CD8(+) T cell subsets contribute to this effect and how they are affected by the peritoneal tumor microenvironment. Here, we provide evidence for a...

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Detalles Bibliográficos
Autores principales: Lieber, Sonja, Reinartz, Silke, Raifer, Hartmann, Finkernagel, Florian, Dreyer, Tobias, Bronger, Holger, Jansen, Julia M., Wagner, Uwe, Worzfeld, Thomas, Müller, Rolf, Huber, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927536/
https://www.ncbi.nlm.nih.gov/pubmed/29721385
http://dx.doi.org/10.1080/2162402X.2018.1424672