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All-atom molecular dynamics of the HBV capsid reveals insights into biological function and cryo-EM resolution limits
The hepatitis B virus capsid represents a promising therapeutic target. Experiments suggest the capsid must be flexible to function; however, capsid structure and dynamics have not been thoroughly characterized in the absence of icosahedral symmetry constraints. Here, all-atom molecular dynamics sim...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927769/ https://www.ncbi.nlm.nih.gov/pubmed/29708495 http://dx.doi.org/10.7554/eLife.32478 |