RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice

Sickle cell disease patients are at increased risk of developing a chronic kidney disease. Endothelial dysfunction and inflammation associated with hemolysis lead to vasculopathy and contribute to the development of renal disease. Here we used a Townes sickle cell disease mouse model to examine rena...

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Detalles Bibliográficos
Autores principales: Khaibullina, Alfia, Adjei, Elena A., Afangbedji, Nowah, Ivanov, Andrey, Kumari, Namita, Almeida, Luis E.F., Quezado, Zenaide M.N., Nekhai, Sergei, Jerebtsova, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927980/
https://www.ncbi.nlm.nih.gov/pubmed/29519868
http://dx.doi.org/10.3324/haematol.2017.180992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927980/
https://www.ncbi.nlm.nih.gov/pubmed/29519868
http://dx.doi.org/10.3324/haematol.2017.180992

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