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Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations

Despite the recent discovery of recurrent driver mutations in chronic lymphocytic leukemia, the genetic factors involved in disease onset remain largely unknown. To address this issue, we performed whole-genome sequencing in 11 individuals with monoclonal B- cell lymphocytosis, both of the low-count...

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Detalles Bibliográficos
Autores principales: Agathangelidis, Andreas, Ljungström, Viktor, Scarfò, Lydia, Fazi, Claudia, Gounari, Maria, Pandzic, Tatjana, Sutton, Lesley-Ann, Stamatopoulos, Kostas, Tonon, Giovanni, Rosenquist, Richard, Ghia, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927998/
https://www.ncbi.nlm.nih.gov/pubmed/29449433
http://dx.doi.org/10.3324/haematol.2017.177212