The novel hsa-miR-12528 regulates tumourigenesis and metastasis through hypo-phosphorylation of AKT cascade by targeting IGF-1R in human lung cancer

Lung cancer cases are increasing yearly; however, few novel therapeutic strategies for treating this disease have been developed. Here the dysregulation between microRNAs and oncogenes or tumour-suppressor genes forms a close connection-loop to the development or progression in human lung carcinogen...

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Detalles Bibliográficos
Autores principales: Jeon, Seong Ho, Yoo, Jung Ki, Kim, Chang Min, Lim, Eun Su, Lee, So Jeong, Lee, Ji Min, Oh, Seung-Hun, Kim, Jin Kyeoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928042/
https://www.ncbi.nlm.nih.gov/pubmed/29712908
http://dx.doi.org/10.1038/s41419-018-0535-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928042/
https://www.ncbi.nlm.nih.gov/pubmed/29712908
http://dx.doi.org/10.1038/s41419-018-0535-8

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