Pathway-based dissection of the genomic heterogeneity of cancer hallmarks’ acquisition with SLAPenrich

Cancer hallmarks are evolutionary traits required by a tumour to develop. While extensively characterised, the way these traits are achieved through the accumulation of somatic mutations in key biological pathways is not fully understood. To shed light on this subject, we characterised the landscape...

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Detalles Bibliográficos
Autores principales: Iorio, Francesco, Garcia-Alonso, Luz, Brammeld, Jonathan S., Martincorena, Iňigo, Wille, David R., McDermott, Ultan, Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928049/
https://www.ncbi.nlm.nih.gov/pubmed/29713020
http://dx.doi.org/10.1038/s41598-018-25076-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928049/
https://www.ncbi.nlm.nih.gov/pubmed/29713020
http://dx.doi.org/10.1038/s41598-018-25076-6

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