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FIV vaccine with receptor epitopes results in neutralizing antibodies but does not confer resistance to challenge

Feline immunodeficiency virus (FIV) is the feline analogue to human immunodeficiency virus (HIV) and utilizes parallel modes of receptor-mediated entry. The FIV surface glycoprotein (SU) is an important target for induction of neutralizing antibodies, and autoantibodies to the FIV binding receptor (...

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Detalles Bibliográficos
Autores principales: Miller, Craig, Emanuelli, Mauren, Fink, Elizabeth, Musselman, Esther, Mackie, Ryan, Troyer, Ryan, Elder, John, VandeWoude, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928050/
https://www.ncbi.nlm.nih.gov/pubmed/29736270
http://dx.doi.org/10.1038/s41541-018-0051-y