G-395A polymorphism in the promoter region of the KLOTHO gene associates with frailty among the oldest-old

Frailty is characterized by a decline in physiological reserve and increased vulnerability. Previous studies have shown that KLOTHO (KL) plays a protective role in several age-related diseases. We hypothesize a probable protective effect of KL on frailty in the elderly population and included a coho...

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Detalles Bibliográficos
Autores principales: Hao, Qiukui, Wang, Yuting, Ding, Xiang, Dong, Biao, Yang, Ming, Dong, Birong, Wei, Yuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057/
https://www.ncbi.nlm.nih.gov/pubmed/29712948
http://dx.doi.org/10.1038/s41598-018-25040-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057/
https://www.ncbi.nlm.nih.gov/pubmed/29712948
http://dx.doi.org/10.1038/s41598-018-25040-4

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