Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration

Inherited retinal degenerations, affecting more than 2 million people worldwide, are caused by mutations in over 200 genes. This suggests that the most efficient therapeutic strategies would be mutation independent, i.e., targeting common pathological conditions arising from many disease-causing mut...

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Detalles Bibliográficos
Autores principales: Lobanova, Ekaterina S., Finkelstein, Stella, Li, Jing, Travis, Amanda M., Hao, Ying, Klingeborn, Mikael, Skiba, Nikolai P., Deshaies, Raymond J., Arshavsky, Vadim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928105/
https://www.ncbi.nlm.nih.gov/pubmed/29712894
http://dx.doi.org/10.1038/s41467-018-04117-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928105/
https://www.ncbi.nlm.nih.gov/pubmed/29712894
http://dx.doi.org/10.1038/s41467-018-04117-8

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