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Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation
The ribosome is indispensable for precisely controlling the capacity of protein synthesis. However, how translational machinery is coordinated to meet the translational demands remains elusive. Here, we identify a nucleolar-specific lncRNA (LoNA), its 5′ portion binds and sequesters nucleolin to sup...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928123/ https://www.ncbi.nlm.nih.gov/pubmed/29712923 http://dx.doi.org/10.1038/s41467-018-04072-4 |