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C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation
Chemoresistance is a major unmet clinical obstacle in ovarian cancer treatment. Epigenetics plays a pivotal role in regulating the malignant phenotype, and has the potential in developing therapeutically valuable targets that improve the dismal outcome of this disease. Here we show that a series of...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928165/ https://www.ncbi.nlm.nih.gov/pubmed/29712898 http://dx.doi.org/10.1038/s41467-018-03590-5 |