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Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1α

This study highlights a novel approach to upregulate mitochondrial biogenesis in neuronal cells. RNS60 is a 0.9% saline solution containing oxygenated nanobubbles that is generated by subjecting normal saline to Taylor-Couette-Poiseuille (TCP) flow under elevated oxygen pressure. RNS60, but not NS (...

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Detalles Bibliográficos
Autores principales: Chandra, Goutam, Kundu, Madhuchhanda, Rangasamy, Suresh B., Dasarathy, Sridevi, Ghosh, Supurna, Watson, Richard, Pahan, Kalipada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928179/
https://www.ncbi.nlm.nih.gov/pubmed/29188424
http://dx.doi.org/10.1007/s11481-017-9771-4