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Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly
Centrosomes are required for faithful chromosome segregation during mitosis. They are composed of a centriole pair that recruits and organizes the microtubule-nucleating pericentriolar material. Centriole duplication is tightly controlled in vivo and aberrations in this process are associated with s...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928214/ https://www.ncbi.nlm.nih.gov/pubmed/29712910 http://dx.doi.org/10.1038/s41467-018-04122-x |