Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly

Centrosomes are required for faithful chromosome segregation during mitosis. They are composed of a centriole pair that recruits and organizes the microtubule-nucleating pericentriolar material. Centriole duplication is tightly controlled in vivo and aberrations in this process are associated with s...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Gupta, Gagan D., Barnabas, Deepak D., Agircan, Fikret G., Mehmood, Shahid, Wu, Di, Coyaud, Etienne, Johnson, Christopher M., McLaughlin, Stephen H., Andreeva, Antonina, Freund, Stefan M. V., Robinson, Carol V., Cheung, Sally W. T., Raught, Brian, Pelletier, Laurence, van Breugel, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928214/
https://www.ncbi.nlm.nih.gov/pubmed/29712910
http://dx.doi.org/10.1038/s41467-018-04122-x

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